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Published on: August 15, 2025
Dumping Syndrome: A Rare Complication Following Nissen Fundoplication
Joana Bernardino Cardoso1, David Sousa1, Cátia Pereira1
1Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Abstract:
Dumping syndrome (DS) is a debilitating entity with gastrointestinal and vasomotor symptoms due to rapid gastric emptying. It is a rare complication of Nissen fundoplication in adults. We report the case of a patient with oesophageal compressive symptoms (dysphagia, oesophageal food impaction and regurgitation) and frequent episodes of sweating and hypoglycaemia after a Nissen fundoplication to treat gastroesophageal reflux disease. Investigation revealed severe oesophagogastric stenosis and excluded insulinoma and other causes of hypoglycaemia. An oral glucose tolerance test and gastric emptying scintigraphy were performed, supporting the diagnosis of DS.
Learning Points:
Dumping syndrome following Nissen fundoplication is a rare condition in adults.Diagnosis requires exclusion of other causes of hypoglycaemia.First-line treatment is based on dietary modifications, although some patients may require pharmacological therapy.
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