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The N-space Episenome unifies cellular information space-time within cognition-based evolution
William B Miller1, John S Torday2, František Baluška3
1Paradise Valley, AZ, USA.
Progress in Biophysics and Molecular Biology
|August 16, 2019
Summary
Cellular homeostasis relies on an integrated information field connecting sensory experiences (senome) with genome and epigenome. This field forms a collective N-space Episenome, crucial for organism-wide information management and development.
Area of Science:
- Cellular Biology
- Systems Biology
- Theoretical Biology
Background:
- Cellular homeostasis is regulated by internal and external condition assessments.
- Cells possess an integrated information field linking sensory input to genetic material.
- Multicellular organisms exhibit collective information management.
Purpose of the Study:
- To propose the N-space Episenome as a novel biological information system.
- To hypothesize the role of the N-space Episenome in morphogenesis and development.
- To define the N-space Episenome as a heritable and transferable cellular projection.
Main Methods:
- Conceptual framework development.
- Integration of cellular senome, genome, and epigenome concepts.
- Postulation of a dual heritable system (biological materiality and N-space Episenome).
Main Results:
- Introduction of the N-space Episenome as a collective information matrix.
- Hypothesized dual heritable system for biological organization.
- Proposed role of N-space Episenome in coordinating multicellular growth and development.
Conclusions:
- The N-space Episenome is a heritable, transferable informational projection essential for holobiont integration.
- Biological organization involves both material and informational (N-space Episenome) heritable systems.
- Morphogenesis arises from interactions between biological materiality and the N-space Episenome.
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