Plummer-Vinson syndrome: improving outcomes with a multidisciplinary approach

Area of Science:

• Gastroenterology
• Rare Diseases

Background:

• Plummer-Vinson syndrome is a rare disorder characterized by dysphagia, iron deficiency anemia, and esophageal webs.
• Existing data is primarily from case reports and small cohort studies, limiting comprehensive understanding.

Purpose of the Study:

• To summarize current knowledge on Plummer-Vinson syndrome.
• To emphasize the importance of surveillance and multidisciplinary care.

Main Methods:

• Literature review of existing case reports and cohort studies.
• Synthesis of clinical information regarding presentation, course, and management.

Main Results:

• Plummer-Vinson syndrome presents with dysphagia, iron deficiency, and esophageal webs.
• While often benign, there is a recognized risk of malignancy, necessitating surveillance.

Conclusions:

• Long-term surveillance is crucial for patients with Plummer-Vinson syndrome due to malignancy risk.
• A multidisciplinary approach involving various healthcare providers is essential for optimal management.