Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Silent supraglottic carcinoma.

L G Close1, M Merkel, J Reisch

  • 1Department of Otorhinolaryngology, University of Texas Health Science Center, Dallas.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|September 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Wide-Positive Matrix Factorisation of particle number size distributions: A new approach accounting for cyclically changing source profiles.

The Science of the total environment·2025
Same author

Adjudicating Mild Cognitive Impairment Due to Alzheimer's Disease as a Novel Endpoint Event in the TOMMORROW Prevention Clinical Trial.

The journal of prevention of Alzheimer's disease·2022
Same author

Diffraction-optimized aperiodic surface structures for enhanced current density in organic solar cells.

Optics express·2022
Same author

[External Quality Assessment of Thick and Thin Blood Smear Slides for the Diagnosis of Malaria in the Lomé and Gulf Health Districts of Togo].

Medecine tropicale et sante internationale·2022
Same author

Use of local anesthesia for inguinal hernia repair has decreased over time in the VA system.

Hernia : the journal of hernias and abdominal wall surgery·2021
Same author

Using explainable machine learning to identify patients at risk of reattendance at discharge from emergency departments.

Scientific reports·2021
Same journal

Otovent Versus Valsalva: Physiological Insights for Diagnostic and Therapeutic Autoinflation in Eustachian Tube Dysfunction.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

CSNK1A1 Mediates Inner Ear Inflammation and Endolymphatic Hydrops in a Lipopolysaccharide-Induced Mouse Model.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Medial Flap Versus Coblation-Assisted Turbinoplasty For Turbinates Hypertrophy: A Prospective Randomized Controlled Trial.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Gender-Affirming Care in Otolaryngology: A State of the Art Review.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Caffeine Consumption and Rhinologic Symptom Severity.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
Same journal

Ethical Considerations in Using the Pernkopf Atlas in Otolaryngology Education Ethics in Practice: Point-Counterpoint.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·2026
See all related articles

Silent squamous cell carcinoma of the supraglottic larynx can evade initial diagnosis. Early detection requires aggressive biopsies guided by computed tomography (CT) findings to overcome diagnostic delays.

Area of Science:

  • Otolaryngology
  • Oncology
  • Radiology

Background:

  • Squamous cell carcinoma of the supraglottic larynx is a significant diagnosis.
  • Initial evaluation typically involves computed tomography (CT) and direct laryngoscopy.
  • Submucosal or inapparent tumors pose diagnostic challenges.

Observation:

  • In a review of 51 patients, 9.8% with untreated supraglottic squamous cell carcinoma had no visible mucosal abnormality on initial CT and laryngoscopy.
  • These patients presented with submucosal disease.
  • Multiple negative biopsies preceded definitive diagnosis in these cases.

Findings:

  • Computed tomography (CT) reliably detects the presence of submucosal disease.
  • Diagnostic delays averaged 19.8 weeks due to initially negative biopsies.

Related Experiment Videos

  • Inapparent neoplasms present unique diagnostic challenges for routine biopsy techniques.

    • Implications:

    • Early diagnosis of "silent" supraglottic cancers is crucial.
    • Aggressive biopsy techniques, informed by CT findings, are necessary for timely diagnosis.
    • Improved diagnostic strategies are needed to reduce delays in detecting these "silent" tumors.