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Updated: Jan 20, 2026

Monitoring Cell-to-cell Transmission of Prion-like Protein Aggregates in Drosophila Melanogaster
Published on: March 12, 2018
A bi-monomeric, nonlinear Becker-Döring-type system to capture oscillatory aggregation kinetics in prion dynamics
Marie Doumic1, Klemens Fellner2, Mathieu Mezache3
1Sorbonne Universités, Inria, Université Paris-Diderot, CNRS, Laboratoire Jacques-Louis Lions, Paris F-75005, France; Wolfgang Pauli Institute, C/O University of Vienna, Austria.
Abstract:
In this article, in order to understand the appearance of oscillations observed in protein aggregation experiments, we propose, motivate and analyse mathematically the differential system describing the kinetics of the following reactions: [Formula: see text] with n finite or infinite. This system may be viewed as a variant of the seminal Becker-Döring system, and is capable of displaying sustained though damped oscillations.
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