Related Experiment Video
Updated: Jan 20, 2026
10:38
Microtubule Plus-End Dynamics Visualization in Huntington's Disease Model based on Human Primary Skin Fibroblasts
Published on: January 8, 2022
3.2K
A model for visual naming based on spatiotemporal dynamics of ECoG high-gamma modulation
Ravindra Arya1, Abbas Babajani-Feremi2, Anna W Byars3
1Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States of America; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, United States of America.
Epilepsy & Behavior : E&B
|August 17, 2019
Summary
Electrocorticography (ECoG) high-gamma modulation (HGM) during visual naming reveals sequential brain activation. This study validates a model of visual naming involving both modular and distributed cortical processing.
Area of Science:
- Neuroscience
- Cognitive Neuroscience
- Neurology
Background:
- Visual naming is a complex cognitive process involving widespread brain networks.
- Understanding the spatiotemporal dynamics of neural activity during visual naming is crucial for diagnosing and treating language disorders.
Purpose of the Study:
- To investigate the spatiotemporal dynamics of electrocorticographic (ECoG) high-gamma modulation (HGM) during visual naming.
- To provide neurophysiologic validation for models of visual naming.
Main Methods:
- Studied 8 patients (aged 4-19 years) with left hemisphere subdural electrodes.
- Mapped propagation of ECoG HGM during overt visual naming using trial-averaged time-frequency analysis.
- Performed group-level synthesis by transforming electrodes to standard space and assigning cortical parcels.
Main Results:
- Identified sequential activation in occipital, temporal, and frontal cortical regions within 1.5 seconds.
- Observed prominent HGM in the glossolaryngeal region (A4tl).
- Noted sustained HGM in ventrolateral premotor cortex after 1.5 seconds.
Conclusions:
- ECoG HGM exhibits a sequential yet overlapping spatiotemporal course during visual naming.
- Findings support a visual naming model integrating modular and distributed cortical processing.
- Results may explain cognitive deficits following surgery near HGM naming sites outside perisylvian language cortex.
Related Concept Videos
02:21Naming Enantiomers
25.7K
The naming of enantiomers employs the Cahn–Ingold–Prelog rules that involve assigning priorities to different substituent groups at a chiral center. Each enantiomer, being a distinct molecule, is assigned a unique name by the Cahn–Ingold–Prelog (CIP) rules, also called the R–S system. The prefix R- or S- attached to the chiral centers in an enantiomer is dependent on the spatial arrangement of the four substituents on the chiral center. The R–S system essentially comprises three...
25.7K
01:19Naming Skeletal Muscles
3.9K
The naming of the approximately 700 muscles in the human body is based on a set of criteria designed to provide descriptive information about each muscle, making it easier to identify and remember them.
The key factors used in naming muscles include:
The key factors used in naming muscles include:
3.9K
01:11Common Names of Aldehydes and Ketones
4.9K
Some common aldehydes and ketones are popularly known by their common names used historically and predate the IUPAC nomenclature.
Common names of aldehydes are derived from the names of their corresponding acid. For instance, the two-carbon aldehyde–acetaldehyde derives its name from the corresponding acid–acetic acid. Similarly, formaldehyde derives its name from formic acid and benzaldehyde from benzoic acid.
Aliphatic ketones are named by suffixing the word “ketone” to the...
Common names of aldehydes are derived from the names of their corresponding acid. For instance, the two-carbon aldehyde–acetaldehyde derives its name from the corresponding acid–acetic acid. Similarly, formaldehyde derives its name from formic acid and benzaldehyde from benzoic acid.
Aliphatic ketones are named by suffixing the word “ketone” to the...
4.9K
02:20Dynamic Equilibrium
61.9K
A reversible chemical reaction represents a chemical process that proceeds in both forward (left to right) and reverse (right to left) directions. When the rates of the forward and reverse reactions are equal, the concentrations of the reactant and product species remain constant over time and the system is at equilibrium. A special double arrow is used to emphasize the reversible nature of the reaction. The relative concentrations of reactants and products in equilibrium systems vary greatly;...
61.9K
01:26Visual System
1.7K
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...
1.7K
01:08Equation of Rotational Dynamics
14.7K
Angular variables are introduced in rotational dynamics. Comparing the definitions of angular variables with the definitions of linear kinematic variables, it is seen that there is a mapping of the linear variables to the rotational ones. Linear displacement, velocity, and acceleration have their equivalents in rotational motion, which are angular displacement, angular velocity, and angular acceleration. Similar to the rotational variables, a mapping exists from Newton's second law of motion...
14.7K