Related Experiment Video
Updated: Jan 20, 2026

A BW Reporter System for Studying Receptor-Ligand Interactions
Published on: January 7, 2019
Structural biology of cell surface receptor-ligand interactions
Steven Moussu1, Julia Santiago1
1The Plant Signaling Mechanisms Laboratory, Department of Plant Molecular Biology, University of Lausanne, 1015 Lausanne, Switzerland.
Abstract:
Plants have evolved unique membrane receptors that interpret native and foreign cues to coordinate plant life and adaptation. This large family of receptor proteins have evolved very diverse ectodomains, acquiring the capacity to sense ligands of very different chemical nature. A mechanistic understanding on how these signaling systems work will help to comprehend and unveil key cell biology questions. This review aims to focus on the latest receptor-ligands interactions and regulatory mechanism that have been structurally characterized, as well as new receptor folds.
Related Concept Videos
Types of Receptors: Cell Surface Receptors
Cell-surface Signaling
Ligand Binding and Linkage
Ligand Binding Sites
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
Internal Receptors
Drug-Receptor Interactions
Several parameters, such as the drug's affinity for its receptor and its efficacy, which is its ability to activate the receptor, determine the drug's effect on the tissue....

