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Updated: Jan 20, 2026
03:57
Electrochemotherapy of Tumours
Published on: December 15, 2008
25.0K
Advances in tumour endoprostheses: a systematic review
Maria A Smolle1, Dimosthenis Andreou2, Per-Ulf Tunn3
1Department of Orthopaedics and Trauma, Medical University of Graz, Austria.
EFORT Open Reviews
|August 20, 2019
Summary
Tumour endoprostheses are crucial for limb salvage in bone and soft tissue sarcomas. Future research should focus on preventing deep infections associated with these advanced prosthetic reconstructions.
Area of Science:
- Orthopaedic surgery
- Oncology
- Biomedical engineering
Background:
- Tumour endoprostheses are vital for limb-salvage surgery in primary bone and soft tissue sarcomas.
- Their use is expanding for treating long bone metastases.
Purpose of the Study:
- To review recent literature (2015-2018) on tumour endoprostheses.
- To summarize current knowledge and identify research gaps.
Main Methods:
- Systematic literature search on PubMed using specific keywords.
- Inclusion of articles from high-impact journals (top 25.9%) in orthopaedics and multidisciplinary sciences.
- Categorization of 53 selected articles into anatomical regions and specific applications.
Main Results:
- The review covered tumour endoprostheses in the shoulder, femur, knee, pelvis, and pediatric cases.
- Survival outcomes of orthopaedic implants were a primary research focus.
- Deep infection risk was a frequently reported concern across studies.
Conclusions:
- Recent studies align with consensus meeting research questions, particularly regarding implant survival.
- Further research is needed to develop preventive strategies for deep infections in tumour endoprosthetic reconstructions.
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