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Comparative in vitro activity of PD 127,391, a new fluorinated 4-quinolone derivative
1Department of Infectious Diseases, University of Umeå, Sweden.
Antimicrobial Agents and Chemotherapy
|August 1, 1988
Abstract:
PD 127,391, a newly developed 4-quinolone chemically similar to ciprofloxacin, was studied in vitro by using agar and broth dilution and two inoculum sizes. PD 127,391 was found to be highly active against gram-negative aerobes, including Pseudomonas aeruginosa and other Pseudomonas spp. Its activity against gram-positive aerobes was better than that of ciprofloxacin.