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Immunocytochemical localization of osteocalcin in human and bovine teeth
I G de Vries1, D Coomans, E Wisse
1Institute of Dentistry, Vrije Universiteit Brussel, Belgium.
Calcified Tissue International
|August 1, 1988
Abstract:
Antisera against bovine and rat osteocalcin were characterized and used for the immunocytochemical visualization of this protein in human and bovine teeth. Osteocalcin immunoreactivity was localized at the dentino-enamel junctions, whereas the major part of the dentin was unstained. These results suggest some involvement of ameloblasts in the deposition of osteocalcin. The low concentration of the protein suggests that it has no direct function in dentin formation.