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Updated: Jan 20, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
Protective effect of β-cyclodextrin on stability of nisin and corresponding interactions involved
Jingjing Li1, Dan Pan1, Juanjuan Yi1
1School of Life Sciences, Zhengzhou University, Zhengzhou, Henan 450001, China.
Abstract:
Nisin has been extensively employed in food industry as an antimicrobial peptide, but the proteolytic degradation and interference by food components resulted in the decrease of its antimicrobial activity. This study intends to explore the protective effect of β-cyclodextrin (β-CD) on nisin and corresponding interactions involved. The antibacterial experiments indicated that the combination of nisin and β-CD could provide a better antibacterial effect on cooked pork meat. Spectral analysis with UV-vis and fluorescence spectroscopy showed that the micro-environment of nisin could be influenced by β-CD. Tricine-SDS-PAGE results exhibited that the combination of nisin and β-CD could delay the degradation of nisin and improve its stability in the presence of trypsin. In sum, the study provided a potential approach to improve the stability of nisin, especially in the presence of trypsin.
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