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Updated: Jan 20, 2026

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
Published on: December 3, 2020
A new light of proteomics in cell biology and toxicology
Tiankui Qiao1, Xiangdong Wang2
1Zhongshan Hospital Jin Shan Hospital Center for Tumor Therapy, Institute for Clinical Science, Shanghai Institute of Clinical Bioinformatics, Shanghai Engineering Research for AI Technology for Cardiopulmonary Diseases; Shanghai Medical College, Fudan University, Shanghai, China.
Abstract:
We expect more studies on proteomics-dominated multi- and trans-omics to paint out a dynamic, multi-level, multi-dimensional picture of molecular mechanisms in the single-cell or targeted cell population to elucidate the regulation of gene-gene, gene-protein, and protein-protein interactions, and define proteome-wide strategy of disease-specific biomarker and therapeutic target discovery and development. We hope that the current issue will be the initiation and stimulation of proteome-based investigations to explore molecular mechanisms in cell functioning and responses to drugs.
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