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Physiologic intracranial calcification with hyperintensity on MR imaging: case report and experimental model
L A Dell1, M S Brown, W W Orrison
1Center for Non-Invasive Diagnosis, University New Mexico, School of Medicine, Albuquerque 87131.
AJNR. American Journal of Neuroradiology
|November 1, 1988
Summary
Intracranial calcification, seen in pseudohypoparathyroidism, can appear as high T1 signal intensity on MRI. Experimental models confirm calcium phosphate suspensions exhibit similar signals, suggesting paramagnetic effects.
Area of Science:
- Neuroradiology
- Biophysics
- Medical Imaging
Background:
- Basal ganglia calcification is a known finding in pseudohypoparathyroidism.
- High signal intensity on T1-weighted Magnetic Resonance (MR) images can be associated with calcification, but the underlying mechanism is not fully understood.