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Updated: Jan 20, 2026

Synthesis and Characterization of Functionalized Metal-organic Frameworks
Published on: September 5, 2014
Covalent Functionalization of Graphene Oxide with a Presynthesized Metal-Organic Framework Enables a Highly Stable
Junhong Fu1, Xiuyun Wang2, Tingting Wang2
1Gold Catalysis Research Center, State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics , Chinese Academy of Sciences , Dalian 116023 , P. R. China.
Abstract:
This paper reports the covalent functionalization of graphene oxide (GO) by a presynthesized metal-organic framework NH2-MIL-101(Fe) via ultrasonication of the two components. The formation of Fe-O covalent bonding in the NH2-MIL-101(Fe)-GO nanohybrid is clearly evidenced, and the covalent bonding still remains after electrochemical reduction. The morphology and structure of the nanohybrid are characterized via scanning electron microscopy, transmission electron microscopy, UV-vis spectroscopy, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, X-ray diffraction, and Raman spectroscopy. The electrode based on electrochemically reduced NH2-MIL-101(Fe)-GO shows ultrastable and high-sensitive performance in simultaneous electrochemical sensing of three purine metabolic derivatives (uric acid, xanthine, and hypoxanthine); in particular, no signal fading is seen even after running for 120 times. The covalent bonding within the nanohybrid is obviously the key to maintain such a stability.
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