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Fragrances: Contact Allergy and Other Adverse Effects
1From Schipslootweg 5 8351 HV, Wapserveen, the Netherlands.
Dermatitis : Contact, Atopic, Occupational, Drug
|August 22, 2019
Summary
Fragrance allergy affects up to 4.5% of adults, with higher rates in those with suspected contact dermatitis. Diagnosis involves patch testing with specific fragrance series to identify common sensitizers in everyday products.
Area of Science:
- Dermatology
- Allergology
- Toxicology
Background:
- Fragrance allergy is a significant health concern.
- Contact with fragrances is common in personal care products.
- Adverse effects from fragrances can impact quality of life.
Purpose of the Study:
- To provide a comprehensive overview of fragrance allergy.
- To discuss the diagnosis, frequency, and clinical presentation of fragrance allergy.
- To identify common fragrance allergens and culprit products.
Main Methods:
- Review of existing literature on fragrance allergy.
- Discussion of diagnostic methods, including patch testing with fragrance series.
- Analysis of epidemiological data on fragrance sensitization.
Main Results:
- Fragrance allergy prevalence is up to 4.5% in the general adult population.
- In patients with suspected contact dermatitis, allergy rates can reach 20-25%.
- Over 150 fragrance ingredients have been identified as contact allergens, with specific compounds like linalool and limonene hydroperoxides being frequent sensitizers.
Conclusions:
- Fragrance allergy is prevalent and diagnosis requires specialized patch testing.
- Common sensitizers are found in deodorants, fine fragrances, and aftershaves.
- While occupational and other adverse effects occur, they are less frequent than contact allergy.
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