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Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
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Carpal tunnel decompression in patients with normal nerve conduction studies.
Samuel P Mackenzie1, Oliver D Stone1, Paul J Jenkins2
1Royal Infirmary of Edinburgh, Edinburgh, UK.
The Journal of Hand Surgery, European Volume
|August 22, 2019
Summary
Patients with carpal tunnel syndrome and normal nerve conduction studies show less improvement after surgery compared to those with abnormal studies. While surgery helps, outcomes are not as significant for this specific group.
Area of Science:
- Orthopedics
- Neurology
- Clinical Outcomes Research
Background:
- Carpal tunnel syndrome (CTS) diagnosis can be challenging, with some patients exhibiting typical symptoms but normal nerve conduction studies (NCS).
- These patients often undergo surgical decompression despite inconclusive NCS findings, typically after conservative treatments fail.
Purpose of the Study:
- To compare the preoperative and 1-year postoperative functional outcomes, measured by QuickDASH scores, in patients with CTS who underwent carpal tunnel decompression.
- Specifically, to evaluate differences between patients with normal NCS and those with abnormal NCS.
Main Methods:
- A retrospective study included 637 patients who underwent carpal tunnel decompression.
- Patients were divided into two groups: those with typical CTS symptoms and normal NCS (n=19), and those with abnormal NCS.
- Preoperative and 1-year postoperative QuickDASH scores were collected and compared between the groups.
Main Results:
- Preoperative QuickDASH scores were similar between the normal NCS (58) and abnormal NCS (54.8) groups.
- At 1 year postoperatively, QuickDASH scores were significantly higher in the normal NCS group (34.9) compared to the abnormal NCS group (21.5).
- The improvement in QuickDASH scores (change from preoperative) was significantly less in the normal NCS group (23.1) than in the abnormal NCS group (33.4).
Conclusions:
- Patients with carpal tunnel syndrome and normal NCS experience significant functional improvement after decompression surgery.
- However, the degree of functional recovery is significantly less pronounced compared to patients with abnormal NCS.
- This suggests that while surgery can be beneficial, the long-term outcomes may differ based on electrodiagnostic findings in CTS.
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