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Endovascular suction thrombectomy for severe cerebral venous sinus thrombosis: A report of two cases
Ahmed A Najjar1, Jameel K Rasheedi2, Khalil I Kurdi3
1Division of Neurosurgery, Faculty of Medicine, King Abdulaziz University, Jeddah, KSA.
Insights
Cerebral venous sinus thrombosis (CVST) can be fatal despite anticoagulation. Endovascular clot removal via suction thrombectomy offers a promising, safe treatment for extensive CVST, improving sinus recanalization and patient outcomes.
Area of Science:
- Neurology
- Vascular Surgery
- Interventional Radiology
Background:
- Cerebral venous sinus thrombosis (CVST) is a serious condition with varied symptoms, from headaches to life-threatening intracranial pressure.
- Standard anticoagulation therapy for CVST has limitations, with a significant mortality risk due to incomplete venous recanalization.
Observation:
- Two cases of extensive CVST with neurological decline despite anticoagulation were reported.
- These patients experienced progressive deterioration necessitating alternative treatment strategies.
Findings:
- Successful endovascular clot removal using suction thrombectomy was performed in both cases.
- Immediate sinus recanalization and rapid radiographic improvement were observed post-procedure.
Implications:
- Endovascular suction thrombectomy presents a potentially effective and safe therapeutic option for severe CVST.
- Further research is required to confirm the efficacy and establish the role of this intervention in CVST management.
Abstract:
Cerebral venous sinus thrombosis (CVST) is a severe clinical condition that manifests with diverse symptoms that can be mild, taking the form of a headache, or can be life-threatening, with raised intracranial pressure and herniation. Despite systemic anticoagulation treatment, CVST still carries a mortality risk of approximately 10% because of the failure of venous recanalization by anticoagulants alone. This paper describes two cases with extensive CVST who presented with progressive neurological deterioration despite adequate systemic anticoagulation treatment. Both patients were successfully treated with endovascular clot removal using suction thrombectomy techniques with immediate recanalization of the sinuses and rapid radiographic improvement. The described therapy appears effective and safe; however, further studies are needed to validate the effectiveness of this treatment.
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