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The p48MW Flow Diverter-Initial Human Experience.

P Bhogal1, C Bleise2, J Chudyk2

  • 1The Royal London Hospital, Whitechapel Road, E1 1BB, London, UK. bhogalweb@aol.com.

Clinical Neuroradiology
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PubMed
Summary
This summary is machine-generated.

The p48MW flow diverter is safe and effective for treating brain aneurysms, including those in small, distal vessels. This study shows good occlusion rates and manageable complications in initial human use.

Keywords:
AneurysmFlow diverterNew devicesP48 MWStent

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Area of Science:

  • Neurosurgery
  • Interventional Radiology
  • Vascular Neurology

Background:

  • Flow diverters are used to treat aneurysms in small parent vessels.
  • The p48MW (p48 Movable Wire) is a novel device designed for vessels 1.75-3 mm in diameter.

Purpose of the Study:

  • To report the initial human experience and outcomes of using the p48MW flow diverter.
  • To evaluate the safety and efficacy of the p48MW for treating intracranial aneurysms.

Main Methods:

  • A monocentric study retrospectively reviewed a prospectively maintained database.
  • Identified patients treated with the p48MW device between January 2017 and January 2019.
  • Collected data on patient demographics, aneurysm characteristics, and follow-up outcomes, including complications.

Main Results:

  • 25 patients with 25 aneurysms were treated; 76% were in the anterior circulation.
  • Complete occlusion was achieved in 75% of aneurysms, with adequate occlusion (RRC grade I or II) in 79.2% at follow-up.
  • A single technical complication and a single clinical complication (4%) occurred, with full recovery. One unrelated death occurred.

Conclusions:

  • The p48MW flow diverter demonstrates safety and effectiveness in treating intracranial aneurysms.
  • The device is suitable for aneurysms in small caliber and distal vessels.