Communication of the Cell Periphery with the Golgi Apparatus: A Hypothesis

The Golgi apparatus plays a central role in the numerous traffic tasks in cells. Whereas the well-investigated chemical signaling is sufficient to explain the information processes in the secretory output of cells, it is insufficient to do that for the substitution of structural elements in the three-dimensional space of the cell. Here we review recent work (Jaross, Front Biosci 23:940-946, 2018) suggesting that molecular vibration patterns of those macromolecules which have to be exchanged are recognized by molecules in the Golgi via resonance of the electromagnetic fingerprints. That results in the activation of specific molecules and induction of the whole substitution process. For bridging intracellular distances, the IR radiation must be coherent. It is discussed that coherence is achieved by chemical reaction during the changing process of the molecule along with the quasicrystalline structure of the neighboring water molecules. Several aspects of the relevance of that signaling to the direct interactions of molecules during various intracellular processes are discussed.