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Updated: Jan 20, 2026

Synthesis of Aptamer-PEI-g-PEG Modified Gold Nanoparticles Loaded with Doxorubicin for Targeted Drug Delivery
Published on: June 23, 2020
Synthesis of Gold Nanoparticle: Peptide-Drug Conjugates for Targeted Drug Delivery
K Kalishwaralal1,2, G Luboshits2,3, M A Firer4,5,6
1Department of Biological Engineering, College of Engineering, Konkuk University, Seoul, Republic of Korea.
Abstract:
Peptide-drug conjugates (PDCs) are being developed for the targeted delivery of drugs to cancer cells. Several approaches are being followed to enhance their stability in biological solutions. Here we describe an effective method to easily couple PDCs to polyethylene-coated gold nanoparticles. We also outline analytical methods to validate the coupling and assays to measure the stability and cytotoxic efficacy of the conjugates.
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