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Updated: Jan 20, 2026

Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
Practical points for applying herpes zoster vaccine recommendations.
Jackie D Brogie1, Joshua H Rumph, Michelle D Chaplin
1Jackie D. Brogie is a pharmacy student at Wingate University School of Pharmacy, Hendersonville, N.C. Joshua H. Rumph is a pharmacy student at Wingate University School of Pharmacy, Hendersonville, N.C. Michelle D. Chaplin is an associate professor at Wingate University School of Pharmacy, Hendersonville, N.C. Nicole A. Drake is an assistant professor at Wingate University Physician Assistant Program, Hendersonville, N.C. Bryan K. Hodge is a family medicine physician and director of rural health initiatives at Mountain Area Health Education Center, Hendersonville, N.C. Ryan E. Owens is an assistant professor at Wingate University School of Pharmacy; Hendersonville, N.C.
The Shingrix vaccine is recommended for adults 50 and older to prevent shingles, replacing the older Zostavax vaccine. This guide helps clinicians implement the latest shingles vaccination guidelines for patient care.
Area of Science:
- Immunology
- Vaccinology
- Public Health
Background:
- Shingles (herpes zoster) is a common and painful condition caused by the varicella-zoster virus.
- The incidence of shingles increases with age, posing a significant health concern for older adults.
- Previous vaccination options existed, but newer recommendations prioritize more effective preventative measures.
Purpose of the Study:
- To inform clinicians about the approval and recommendation of the recombinant zoster vaccine (Shingrix).
- To provide practical guidance for the effective implementation of shingles vaccination in patients aged 50 and above.
- To highlight the CDC's updated recommendations favoring Shingrix over Zostavax.
Main Methods:
- Review of recent vaccine approval and CDC recommendations.
- Analysis of clinical considerations for vaccine administration.
- Guidance on patient counseling and management.
Main Results:
- Recombinant zoster vaccine (Shingrix) is approved for individuals aged 50 years and older.
- The CDC now recommends Shingrix over the live zoster vaccine (Zostavax).
- Practical strategies are essential for clinicians to apply these recommendations.
Conclusions:
- Shingrix represents a significant advancement in shingles prevention for older adults.
- Clinician adherence to updated guidelines is crucial for maximizing vaccine effectiveness.
- Effective patient management ensures optimal outcomes in shingles prevention programs.
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