Related Experiment Video
Updated: Jan 20, 2026

A Web-Based Workflow for Selecting Gene- and Tissue-Specific Enhancers
Published on: July 18, 2025
Highly selective visual sensing of copper based on fluorescence enhanced glutathione-Au nanoclusters
Xing-Juan Li1, Yu Li1, An-Yong Liu1
1Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
Abstract:
A blue emission glutathione stabilized Au nanoclusters prepared by an Au/Histidine complex with ligand-exchanges method was used for sensing of copper ions. We found that the glutathione stabilized Au NCs which has fluorescence emission hundred times higher than the Au/Histidine complex and has a highly selective fluorescence quenching response to copper ion. Other common metal ions, such as mercury, lead, iron and zinc, which could obviously quench or enhance the fluorescence of Au/Histidine complex, do not interfere the sensing of copper using glutathione stabilized Au nanocluster. The possible quenching mechanism and the dynamic quenching process for copper detection were also discussed. The results indicated that copper in the range from 0.5 to 300.0μM could be linearly detected and the detection could be finished quickly in 5min. A visual detection method for copper ion that may be used to fast warn copper pollution in waters by naked eyes observation was also be developed using the glutathione stabilized Au NCs probe.
Related Concept Videos
The Sense of Self: Reflected Self-Appraisal and Social Comparison
Self-Evaluation: Self-Enhancement and Self-Verification
Introduction to Special Senses
Tactile and Chemical Senses
Phase II Reactions: Glutathione Conjugation and Mercapturic Acid Formation
Several distinctive characteristics distinguish glutathione conjugation from other phase II...
What is Natural Selection?

