Related Experiment Video
Updated: Jan 20, 2026

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
Published on: August 1, 2018
Challenges and Opportunities in Changing Data Structures of Clinical Document Archives from HL7-V2 to FHIR-Based
Jochen Zohner1, Kurt Marquardt1, Henning Schneider1
1Department of Medical Informatics, Justus Liebig University, Giessen, Hesse, Germany.
Abstract:
In 2018, a major replacement of clinical applications took place at the University Hospital of Giessen. One key part was the clinical document archive containing a vast collection of clinical data from the last 30 years. The aim of this sub-project was to move all data to a new system without any loss, while maintaining all functionality and all communication interfaces. This project successively resulted in a complete paradigm change in document storage. While the legacy clinical data repository (LCDR) was designed according to HL7-V2 principles, the replacement resulted in an HL7-FHIR implementation. The aim of this work is to discuss the differences between both approaches, the obstacles that appeared during migration, but also the opportunities resulting from the new philosophy, especially as far as the impact on the use of scientific data is concerned.
More Related Videos
09:19Measuring the Structure, Composition, and Change of Underwater Environments with Large-area Imaging
Published on: April 18, 2025
07:43Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
Published on: July 29, 2017
Related Concept Videos
Archival Research
Weak Base Solutions
Strong Acid and Base Solutions
Global Climate Change
Statistical Software for Data Analysis and Clinical Trials
Solution Composition During Acid/Base Titrations
The α0 and α1 values...