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Updated: Jan 20, 2026

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Development of a high-throughput γ-H2AX assay based on imaging flow cytometry

Younghyun Lee1,2, Qi Wang3, Igor Shuryak3

  • 1Center for Radiological Research, Columbia University Irving Medical Center, 630 West 168th St, New York, NY, 10032, USA. younghyun.lee.0123@gmail.com.

Radiation Oncology (London, England)
|August 24, 2019
PubMed
Summary

This study developed a rapid, high-throughput imaging flow cytometry assay to measure DNA double-strand break (DSB) repair kinetics. The assay quantifies individual radiosensitivity, aiding precision medicine in radiotherapy.

Keywords:
DNA repair kineticsHigh throughputHuman lymphocytesImaging flow cytometryIonizing radiationRadiation sensitivity

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