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Paediatric Dentists Treating Children on Bisphosphonates: A Cross-Sectional Questionnaire-Based Study
Jeremy Lau1, Lei Ng2, Allauddin Siddiqi3
1Drs. Lau, is a postgraduate student in Periodontology, at the School of Dentistry and Oral Health, Griffith University, Gold Coast, Queensland, Australia.
Pediatric dentists in Australia and New Zealand show good communication regarding bisphosphonate therapy but vary in management strategies for children on these medications, particularly concerning bisphosphonate-related osteonecrosis of the jaw (BRONJ).
Area of Science:
- Pediatric Dentistry
- Pharmacology
- Oral Medicine
Background:
- Bisphosphonates are increasingly used in pediatric patients for various conditions.
- Management of dental care for children on bisphosphonates requires specific protocols to mitigate risks like bisphosphonate-related osteonecrosis of the jaw (BRONJ).
- Understanding current practices among pediatric dentists is crucial for developing consistent guidelines.
Purpose of the Study:
- To assess the knowledge and management strategies of pediatric dentists in Australia and New Zealand regarding children undergoing bisphosphonate therapy.
- To evaluate the consistency of management approaches for these patients, particularly concerning BRONJ prevention and treatment.
Main Methods:
- A 19-item online questionnaire was distributed to pediatric dentists in Australia and New Zealand.
- The survey covered demographics, knowledge of BRONJ, professional role and confidence, and management strategies for pediatric patients on bisphosphonates.
- A response rate of 43% was achieved, with 53 valid responses analyzed.
Main Results:
- 40% of surveyed pediatric dentists were involved in managing children on bisphosphonates, while 47% had no role.
- 37% recognized the importance of completing invasive dental treatment before initiating bisphosphonate therapy, with 13% unsure.
- While 83% had received information on BRONJ, significant variability existed in approaches to antibiotic prophylaxis, chlorhexidine use, and drug holidays.
Conclusions:
- A consensus exists regarding the importance of communication between dentists and physicians for children on bisphosphonates.
- However, considerable controversy and lack of uniformity were observed in other critical management strategies related to bisphosphonate therapy.
- Further research and guideline development are needed to standardize care and improve outcomes for pediatric patients on bisphosphonates.
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