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Maxillary sinus floor elevation using Beta-Tricalcium-Phosphate (beta-TCP) or natural bone: same inflammatory

Justine Loin1, Jean-Daniel Kün-Darbois2,3, Bernard Guillaume4,5

  • 1Service de Chirurgie Maxillo-faciale et stomatologie, CHU d'Angers, 4 rue Larrey, 49933, Angers Cedex, France.

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|August 24, 2019
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Beta-tricalcium phosphate (β-TCP), a synthetic biomaterial, shows comparable sinus membrane edema to natural bone after sinus lift surgery. This makes β-TCP a viable alternative for augmenting bone volume in the maxilla for dental implants.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Biomaterials Science
  • Regenerative Dentistry

Background:

  • Sinus elevation is crucial for dental implant placement in atrophic maxilla.
  • Autogenous bone, the gold standard, has limitations like quantity and donor site morbidity.
  • Synthetic biomaterials like beta-tricalcium phosphate (β-TCP) are alternatives, with expected low inflammatory response.

Purpose of the Study:

  • To compare the degree of sinus mucosa edema after sinus lift surgery using synthetic biomaterial (β-TCP) versus natural bone.
  • To evaluate β-TCP as a potential alternative to autogenous bone in sinus augmentation procedures.

Main Methods:

  • Retrospective study of 40 sinuses (20 patients) divided into β-TCP, natural bone, and control groups.
  • Computed tomography (CT) scans analyzed pre- and post-operatively to measure sinus membrane thickness (SM.Th).
  • Twelve measurements per sinus were averaged to determine SM.Th, indicating mucosal edema.

Main Results:

  • Sinus membrane thickness (SM.Th) increased significantly post-operatively in both β-TCP and natural bone groups compared to controls and pre-operative measurements.
  • No significant difference in post-operative SM.Th was observed between the β-TCP and natural bone groups.
  • The synthetic biomaterial β-TCP induced a similar degree of mucosal edema as natural bone.

Conclusions:

  • Synthetic biomaterial β-TCP elicits a comparable inflammatory response (edema) to natural bone during sinus lift procedures.
  • β-TCP represents a promising and effective alternative to autogenous bone for maxillary sinus augmentation, offering reduced donor site morbidity.