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Published on: February 6, 2021
Self-propelled micromachines for analytical sensing: a critical review
Marta Pacheco1, Miguel Ángel López1,2, Beatriz Jurado-Sánchez3,4
1Department of Analytical Chemistry, Physical Chemistry and Chemical Engineering, University of Alcala, 28871, Alcala de Henares, Spain.
Self-propelled micromotors are tiny devices that move autonomously for analytical sensing. This review covers their evolution into sophisticated systems for advanced analytical chemistry applications.
Area of Science:
- Analytical Chemistry
- Nanotechnology
- Materials Science
Background:
- Self-propelled micromotors are micro/nanoscale devices capable of autonomous movement in solution.
- They convert stimuli into mechanical work, enabling diverse operations and applications.
- Their small dimensions offer novel solutions for complex analytical challenges.
Purpose of the Study:
- To provide a critical overview of early developments and future prospects of self-propelled micromotors.
- To discuss their application in analytical sensing and biosensing strategies.
- To highlight progress in in vivo biosensing and integration into analytical instrumentation.
Main Methods:
- Review of early electrophoretic and bubble-propelled nanomotors.
- Analysis of advancements towards sophisticated all-in-one analytical systems.
- Examination of current progress in in vivo biosensing and device integration.
Main Results:
- The field has evolved from limited nanomotors to advanced systems with integrated sensing.
- Micromotors are becoming sophisticated analytical tools with broad applications.
- Progress is being made towards in vivo applications and fully functional devices.
Conclusions:
- Self-propelled micromachines represent a new paradigm in analytical chemistry.
- Future prospects include advanced in vivo biosensing and integrated analytical instrumentation.
- These tiny moving objects offer significant potential for future analytical solutions.
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