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Robot-Assisted Kidney Transplantation
Published on: July 19, 2021
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Adherence profiles in kidney transplant patients: Causes and consequences
Claire Villeneuve1, Annick Rousseau2, Jean-Phillipe Rerolle3
1CHU Limoges, Department of Pharmacology, Toxicology and Centre of Pharmacovigilance, F-87000 Limoges, France; INSERM, UMR-1248, F-87000 Limoges, France.
Patient Education and Counseling
|August 27, 2019
Summary
Kidney transplant patients
Area of Science:
- Nephrology
- Transplantation Medicine
- Psychology
Background:
- Patient adherence is crucial for kidney transplant success.
- Understanding adherence dynamics post-transplant is vital for long-term outcomes.
Purpose of the Study:
- To longitudinally explore adherence patterns in kidney transplant recipients.
- To identify factors associated with adherence and its impact on patient outcomes.
Main Methods:
- Two cohorts of kidney transplant recipients (EPIGREN and EPHEGREN) were studied.
- Adherence was measured repeatedly using the Morisky-Green-Levine 4-Item Medication Adherence Scale.
- Latent class and mixed-effects modeling analyzed adherence time-profiles.
Main Results:
- Two adherence classes were identified: 85% were adherent, while a smaller group showed declining adherence.
- Poorer adherence was linked to younger age, more depression episodes, and lower mental health quality of life.
- The adherent group experienced longer survival without acute rejection episodes.
Conclusions:
- Poor adherence risk in renal transplant patients can be identified early, within one month post-transplantation.
- Routine monitoring tools can help detect at-risk patients for timely intervention.
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