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[Inhibition of post-partum physiological milk secretion by caffeine dihydroergocryptine and dihydroergotoxine]
M Elsener1, M Ferrafiat, M de Bruyn
1Clinique Mutualiste des Eaux Claires de Grenoble.
Abstract:
Starting from the structural analogy between bromo-ergocryptine (Parlodel) and dihydroergocryptine caffeine (Vasobral), as well as with dihydroergotoxine (Hydergine), the authors decided to test the efficacy of the last two products in inhibiting post-partum physiological milk secretion. Twelve patients will be treated with either one of the two products, with a clinical and biological efficacy (serum prolactin level assay) which is comparable to that found in the literature regarding Parlodel. This study confirm the results obtained in a study of the inhibition of hyper-prolactinemia of other origin, by the same authors.