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Updated: Jan 20, 2026

Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome ARDS
Published on: September 7, 2016
Cardiac Dysfunction in Acute Respiratory Distress Syndrome
Sheng Fu1, Sarumathi Thangavel, Valentyna Ivanova
1Department of Cardiovascular Medicine, Allegheny General Hospital, Part of the Allegheny Health Network, Pittsburgh, Pennsylvania.
Abstract:
Acute respiratory distress syndrome is a heterogenous condition with significant mortality and limited therapeutic options. Although hypoxic respiratory failure tends to be the hallmark of the disease, there can be significant cardiac compromise, particularly in the right ventricle. Echocardiography plays an important role in the early diagnosis and recognition of right ventricular dysfunction. Treatment of said dysfunction with mechanical ventilation strategies and therapies such as inhaled nitric oxide or extracorporeal membrane oxygenation remain poorly studied but offer potential salvage strategies.
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