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Myocardial protection with complementary dose of modified Del Nido cardioplegia during heart transplantation

Michele Gallo1, Jaimin R Trivedi1, Mark S Slaughter1

  • 1Department of Cardiovascular and Thoracic Surgery, University of Louisville School of Medicine, Louisville, Kentucky.

Journal of Cardiac Surgery
|August 27, 2019
PubMed

Insights

Modified Del Nido Cardioplegia offers a potential solution for myocardial protection during heart transplantation implantation. This preliminary case series explores its use as a complementary dose in recipients.

Area of Science:

  • Cardiology
  • Transplantation Medicine
  • Cardiovascular Surgery

Background:

  • Myocardial protection is crucial during heart transplantation.
  • Standard protocols involve an initial dose of preservation solution during donor heart harvesting.
  • There is no established consensus on complementary cardioplegia administration during recipient implantation.

Observation:

  • A preliminary case series was conducted.
  • Modified Del Nido Cardioplegia was administered as a complementary dose.
  • Administration occurred at the time of donor heart implantation into the recipient.

Findings:

  • The study describes the use of modified Del Nido Cardioplegia.
  • This approach was employed as a complementary myocardial protection strategy.
  • The context was donor heart implantation in recipients.

Implications:

  • This case series suggests a potential method for enhancing myocardial protection during heart transplantation.
  • Further research is warranted to validate the efficacy and safety of modified Del Nido Cardioplegia in this setting.
  • Establishing consensus on complementary cardioplegia management could improve transplant outcomes.

Keywords:
donor heart preservationheart transplantationmodified Del Nido cardioplegiamyocardial protection

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