Current State of Platinum Complexes for the Treatment of Advanced and Drug-Resistant Breast Cancers
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Updated: Jan 20, 2026

Author Spotlight: Unveiling the Role of TMOD3 in Platinum Resistance and Immune Infiltration in Ovarian Cancer
Published on: August 2, 2024
Bernhard Biersack1, Rainer Schobert2
1Organic Chemistry Laboratory, Bayreuth, Germany. bernhard.biersack@yahoo.com.
Abstract:
Breast cancer represents the major cause of death in female cancer patients. New efficient treatments are desperately needed, particularly especially for patients suffering from advanced stages and metastases, or those who are no longer responding to the clinically established drugs such as cisplatin or carboplatin. New promising therapy regimens and platinum complexes have emerged over the last few years that displayed efficacy in advanced platinum- and/or drug-resistant breast tumors and metastases. This chapter provides an overview of the latest developments in the field of platinum-based drugs against advanced and resistant breast cancers since 2013.
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