Ligand-Driven and Full-Color-Tunable Fiber Source: Toward Next-Generation Clinic Fiber-Endoscope Tomography with...

In many biomedical applications, broad full-color emission is important, especially for wavelengths below 450 nm, which are difficult to cover via supercontinuum generation. Single-crystalline-core sapphires with defect-driven emissions have potential roles in the development of next-generation broadband light sources because their defect centers demonstrate multiple emission bands with tailored ligand fields. However, the inability to realize high quantum yields with high crystallinity by conventional methods hinders the applicability of ultra-broadband emissions. Here, we present how an effective one-step fiber-drawing process, followed by a simple and controllable thermal treatment, enables a low-loss, full-color, and crystal fiber-based generation with substantial color variability. The broad spectrum extends from 330 nm, which is over 50 nm further into the UV region than that in previously reported results. The predicted submicrometer spatial resolutions demonstrate that the defect-ligand fields are potentially beneficial for achieving in vivo cellular tomography. It is also noteworthy that the efficiency of the milliwatt-level full-color generation, with an optical-to-optical efficiency of nearly 5%, is the highest among that of the existing active waveguide schemes. In addition, direct evidence from high-resolution transmission electron microscopy together with electron energy loss spectroscopy and crystal-field ligands reveals an excellent crystalline core, atomically defined core/cladding interfacial roughness, and significant enhancements in new laser-induced electronic defect levels. Our work suggests an inexpensive, facile, and highly scalable route toward achieving cellular-resolution tomographic imaging and represents an important step in the development of endoscope-compatible diagnostic devices.