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Updated: Jan 20, 2026
Synthesis and Mass Spectrometry Analysis of Oligo-peptoids
Published on: February 21, 2018
Fast and Green Synthesis of an Oligo-Hydrocaffeic Acid-Based Adhesive
Ali Ghadban1, Harini Mohanram1, Ali Miserez1,2
1Centre for Biomimetic Sensor Science, School of Materials Science and Engineering, Nanyang Technological University (NTU), 50 Nanyang Avenue, Singapore 637553.
Abstract:
A green, mussel-inspired bioadhesive based on oligomerization of hydrocaffeic acid was synthesized in water by an ultrafast one-step reaction in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide as an activating agent. The resulting oligomers exhibited strong wet adhesion when applied to different substrates including glass, stainless steel, and aluminum. Compared to most commercial adhesives, this bioinspired adhesive is produced via a sustainable and green process, i.e., aqueous-based synthesis, one-step reaction, and in the absence of any purification step to obtain the final functional adhesive.
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