Insulin-and-Glucagon Artificial Pancreas Versus Insulin-Alone Artificial Pancreas: A Short Review

Ahmad Haidar1,2,3

  • 1Department of Biomedical Engineering, McGill University, Montreal, Quebec, Canada.

Related Concept Videos

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas04:41

Glucose-Stimulated Insulin Secretion via Perfusion through the Mice Vasculature with an Intact Pancreas

Here, we provide details on performing glucose-stimulated insulin secretion (GSIS) via perfusion through the mice vasculature with an intact pancreas as an additional technique to assess the endocrine pancreatic function with reduction of possible...
918
Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation09:01

Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Pancreas Allografts before Transplantation

Normothermic ex vivo machine perfusion (NEVP) has scarcely been explored for the preservation of pancreas allografts. We present an innovative preservation technique for pancreas allografts before transplantation.
2.5K
Stabilized Window for Intravital Imaging of the Murine Pancreas07:12

Stabilized Window for Intravital Imaging of the Murine Pancreas

We present a protocol for the surgical implantation of a stabilized indwelling optical window for subcellular-resolution imaging of the murine pancreas, allowing serial and longitudinal studies of the healthy and diseased...
2.7K
High Resolution 3D Imaging of the Human Pancreas Neuro-insular Network09:54

High Resolution 3D Imaging of the Human Pancreas Neuro-insular Network

Here, we present a protocol to image human pancreas sections in three dimensions (3D) using optimized passive clearing methods. This manuscript demonstrates these procedures for passive optical clearing followed by multiple immunofluorescence staining to identify key elements of the autonomic and sensory neural networks innervating human islets.
11.5K
Generating Human Pancreatic Tissue Slices to Study Endocrine and Exocrine Pancreas Physiology08:16

Generating Human Pancreatic Tissue Slices to Study Endocrine and Exocrine Pancreas Physiology

This protocol describes how to generate human pancreas slices from deceased organ donors to study cell function under near-physiological conditions. This innovative approach enables the investigation of normal and structurally damaged islets and the intricate interplay between endocrine and exocrine compartments.
2.1K
Effective Isolation of Functional Islets from Neonatal Mouse Pancreas07:04

Effective Isolation of Functional Islets from Neonatal Mouse Pancreas

We describe a protocol herein for isolating intact islets from neonatal mice. Pancreata were partially digested with collagenase, followed by washing and hand picking. 20 - 80 islet clusters can be obtained per pancreas from newly born mice, which are suitable for several islet...
10.9K