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Updated: Jan 20, 2026

Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications
Published on: May 31, 2018
[Decellularization of organs and tissues]
O I Startseva1, M E Sinelnikov1, Yu V Babayeva1
1Sechenov First Moscow State Medical University, Moscow, Russia.
Abstract:
The use of allogenic materials in reconstructive surgery is of great scientific interest due to high availability of donor tissues. The positive aspects of allogenous tissue transplantation are complicated by the histological incompatibility of donor tissue and recipient organism. This incompatibility results hypersensitivity reaction towards the allogenous transplant followed by rejection of allogenic tissue and even death in some cases. Cellular biological incompatibility may be managed by decellularization of allogenous organs and tissues prior to transplantation. The improvement of decellularization techniques will facilitate application of allogenous tissues in complex reconstructive procedures and significantly increase the capabilities of reconstructive surgery.
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