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Updated: Jan 20, 2026

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion
Published on: January 15, 2016
Development of and recent advances in asymmetric A3 coupling
Balaji V Rokade1, James Barker, Patrick J Guiry
1Centre for Synthesis and Chemical Biology (CSCB), School of Chemistry, University College Dublin (UCD), Belfield, Dublin 4, Ireland. p.guiry@ucd.ie.
Abstract:
Asymmetric A3 coupling has emerged as an important class of reactions to synthesise chiral propargylamines. In this tutorial review, an up to date progress of this reaction, with significant recent advancements in terms of ligand development, is presented. Applications of asymmetric A3 coupling in natural product synthesis and in tandem processes are also discussed.
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