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Updated: Jan 20, 2026

Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Treatment of refractory bullous pemphigoid with IFN-α-2b: A case report
Tianjing Wang1, Yingping Xu1, Yingying Ren1
1Dermatology Hospital of Southern Medical University, Guangzhou, China.
Abstract:
We reported a patient with refractory bullous pemphigoid (BP), who had a higher level of eosinophils and serum IgE. The case showed less response to various therapies. Edematous erythema and new blisters appeared constantly. Considering IFN-α-2b treatment could significantly decrease blood eosinophils, we therefore expected that IFN-α-2b could be effective in the treatment of BP. After treated with IFN-α-2b, the patient's good response to the treatment suggested our hypothesis.
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