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Updated: Jan 20, 2026

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
Kaposi Sarcoma Updates
Shervin A Etemad1, Anna K Dewan1
1Department of Dermatology, Vanderbilt University Medical Center, 719 Thompson Lane, One Hundred Oaks, Suite 26300, Nashville, TN 37204, USA.
Abstract:
Kaposi sarcoma (KS) is an angioproliferative mesenchymal neoplasm caused by Kaposi sarcoma-related herpesvirus. This review outlines our current understanding of the epidemiology, pathogenesis, clinical presentation, and staging for this disease. Recent research has informed a more comprehensive understanding of the epidemiology of KS in the post-antiretroviral therapy era, and highlights the continued need to better characterize the African endemic subtype. Advances in clinical oncology, including checkpoint inhibitors and new skin-directed therapies, have translated into exciting new developments for the future of KS treatment options.
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