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Updated: Jan 20, 2026

Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
Does utilization of electronic cigarettes facilitate smoking cessation compared to other interventions?
Sarah Wolf1, Senushi O'Sullivan1, Roselynn Dean1
1(Great Plains Family Medicine Residency Program, Oklahoma City, OK).
Clinical Question:
Does utilization of electronic cigarettes facilitate smoking cessation compared to other interventions?
Authors:
Sarah Wolf MD, PGY-1; Senushi O'Sullivan MD, PGY-2;Roselynn Dean MD, PGY-3; Tomas Owens MD.
Faculty Mentor:
Tomas Owens, MD.
Residency Program:
Integris Great Plains Family Medicine Residency Program, Oklahoma City, Oklahoma.
Answer:
Debatable. With conflicting data and some evidence of e-cigarettes leading to on-going nicotine use, there is not a clear benefit to utilizing e-cigarettes for smoking cessation.
Level Of Evidence For The Answer:
B.
Search Terms:
smoking cessation, electronic cigarettes, e-cigarettes.
Date Search Was Concluded:
24 April 2019 Inclusion and Exclusion Criteria.
Inclusion Criteria:
Studies directly comparing smoking cessation with utilization of electronic cigarettes compared to control group.
Exclusion Criteria:
Studies that were systematic reviews, published since 2015, and studies comparing smoking cessation with anything other than electronic cigarettes.
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