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Updated: Jan 20, 2026

Isolation of Type I and Type II Pericytes from Mouse Skeletal Muscles
Published on: May 26, 2017
Adult-Type Rhabdomyoma of the Omohyoid Muscle.
Brian H Cameron1, Kyle Hannabass2, Anuradha Kanungo3
1Keck School of Medicine of USC, Los Angeles, CA, USA.
Extracardiac rhabdomyomas are rare benign tumors, often found in the head and neck. This case highlights diagnostic challenges and successful surgical treatment of a neck mass, emphasizing the importance of considering this diagnosis.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Rhabdomyomas are benign mesenchymal tumors resembling skeletal muscle.
- Extracardiac rhabdomyomas, particularly the adult subtype, predominantly occur in the head and neck region.
- Diagnosis can be difficult due to potential misinterpretation of fine-needle aspiration (FNA) and core biopsies.
Observation:
- A case of a slowly enlarging left neck mass in the strap musculature of a 45-year-old male is presented.
- Multiple FNA and core biopsies were inconclusive, initially raising suspicion for sampling error or rhabdomyosarcoma.
- Excisional biopsy revealed a hypertrophied left inferior belly of the omohyoid muscle.
Findings:
- Histological analysis confirmed the diagnosis of an adult-type extracardiac rhabdomyoma.
- Complete surgical excision is the established gold standard treatment for these benign tumors.
- The patient experienced an uncomplicated recovery following surgical intervention.
Implications:
- Benign extracardiac rhabdomyoma should be included in the differential diagnosis for head and neck skeletal muscle tumors.
- Accurate diagnosis is crucial to avoid unnecessary aggressive treatments and guide appropriate patient management.
- Consideration of this rare entity aids in effective patient counseling and surgical planning.
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