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Severe ovarian hyperstimulation syndrome. Case reports.

O Magnus¹, T Tanbo, T Henriksen

¹Department of Gynecology and Obstetrics, National Hospital, University of Oslo, Norway.

Acta Europaea Fertilitatis

|March 1, 1988

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Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ovulation induction, often linked to fertility treatments like IVF. Understanding its causes and treatments is crucial due to increasing incidence.

Area of Science:

Reproductive Endocrinology
Gynecology

Background:

Ovarian hyperstimulation syndrome (OHSS) is a significant risk associated with ovulation induction therapies.
The increasing use of assisted reproductive technologies like in vitro fertilization (IVF) and gamete intra fallopian transfer (GIFT) contributes to a rise in OHSS cases.

Observation:

OHSS can occur with various ovulation induction agents, including human menopausal gonadotropins (hMG), follicle-stimulating hormone (FSH), and clomiphene (CC).
It has also been reported in pregnancies with hydatiform mole, chorioepithelioma, and multiple gestations unrelated to fertility treatments.
Follicular aspiration, a potential intervention, did not alter the clinical course in two presented cases of OHSS.

Findings:

The pathophysiology of OHSS requires further elucidation to understand its triggers.

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Effective treatment strategies for established OHSS need to be clearly defined.

Implications:

Increased incidence of OHSS necessitates a deeper understanding of its mechanisms and management.
This highlights the importance of monitoring patients undergoing ovulation induction for potential OHSS development and complications.