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Updated: Jan 20, 2026

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling
Published on: October 8, 2019
Recognition of mixed-sequence DNA targets using spermine-modified Invader probes
Shiva P Adhikari1, Raymond G Emehiser, Saswata Karmakar
1Department of Chemistry, University of Idaho, 875 Perimeter Drive MS2343, Moscow, ID 83844-2343, USA. hrdlicka@uidaho.edu.
Abstract:
Double-stranded oligodeoxyribonucleotides with +1 interstrand zipper arrangements of 2'-O-(pyren-1-yl)methyl-RNA monomers are additionally activated for highly specific recognition of mixed-sequence DNA targets upon incorporation of non-nucleotidic spermine bulges.
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