Related Experiment Video
Updated: Jan 20, 2026
Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity AIDN: A Translational Neuroscience Approach
Published on: June 11, 2017
Lithium-Induced Neurotoxicity: A Case Study
Melissa A Schneider1, Sonya S Smith
1Sonya S. Smith, BSN RN, is Staff Nurse, Wellspan York Hospital, York, PA.
Background:
In patients presenting with neurological deficits, identifying the cause can be challenging.
Methods:
This case study discusses a condition that is not commonly seen.
Discussion:
Although lithium toxicity syndrome is not as familiar as other causes of neurological issues, this should be considered for any patient who presents with unexplained neurological deficits and a history of taking this medication.
Conclusion:
If toxicity is not recognized early, the patient can be left with irreversible neurological symptoms, also known as syndrome of irreversible lithium-effectuated neurotoxicity, which impacts quality of life or can even cause death.
Related Concept Videos
06:38Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity (AIDN): A Translational Neuroscience Approach
08:23Adaptation of Microelectrode Array Technology for the Study of Anesthesia-induced Neurotoxicity in the Intact Piglet Brain
04:06An Assay to Study Effect of Test Compound against PolyQ-Mediated Neurotoxicity in Worms
09:02Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing
10:41Three-electrode Coin Cell Preparation and Electrodeposition Analytics for Lithium-ion Batteries
08:37Microglia as a Surrogate Biosensor to Determine Nanoparticle Neurotoxicity