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Updated: Aug 19, 2026

Modeling Biological Membranes with Circuit Boards and Measuring Electrical Signals in Axons: Student Laboratory Exercises
Published on: January 18, 2011
Temperature dependence of conduction velocity in myelinated frog nerve
Abstract:
The temperature dependence of the conduction velocity of excitation was investigated in frog sciatic nerve trunk. A specific electronic circuitry was used to measure the time of conduction between two electrodes with an accuracy of +/- microseconds in the temperature range of 5--30 degrees C. Our experiments have proved that the conduction velocity depended linearly on temperature. The slope of the curve was similar at both increasing and decreasing temperature, and "hysteresis" occurred only if irreversible changes occurred in the preparation during the experimental procedure.
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