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Updated: Jan 20, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
The Unique Role of Fluorodeoxyglucose-PET in Radioembolization
Remco Bastiaannet1, Martin A Lodge2, Hugo W A M de Jong3
1Department of Radiology and Nuclear Medicine, University Medical Center, Huispost E01.132, Postbus 85500, Utrecht 3508 GA, Netherlands; The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 601 N. Caroline St., Baltimore, MD 21287, USA.
Abstract:
Recent research into the efficacy of radioembolization has brought this field to an interesting position, in which fluorodeoxyglucose (FDG)-PET/CT is being used extensively for prognosis and response assessment, as well as a tool to define viable tumor volumes for the use in dosimetry. As such, there is an overlap with existing techniques used in radiotherapy; however, many are very specific to the radioembolization paradigm. This article describes the current state-of-the-art of the use of FDG-PET/CT for patient selection, prognosis, treatment evaluation, and as a research tool into absorbed dose-response relationships in radioembolization.
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