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Updated: Jan 20, 2026

Isolation and Culture of Primary Human Gingival Epithelial Cells using Y-27632
Published on: November 6, 2021
An unusual case of recurrent gingival hirsutism
Khrystyna Zhurakivska1, Giorgio Toni2, Gregorio Laino3
1Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.
Objectives:
The occurrence of hairs in the oral cavity is an exceedingly rare event, with unknown etiology. A literature review found only 5 cases, most of which described a single hair localized in various sites of the oral cavity. The aim of the present article is to report a follow-up presentation of a rare case of oral hirsutism detected in a young woman.
Case Presentation:
A 25-year-old woman with previously diagnosed polycystic ovary syndrome returned to our attention 6 years after the first intervention, complaining of the presence of oral hairs. Extraoral facial examination revealed the presence of exuberant hair on the chin and neck regions. Intraoral examination showed some brown hair, similar to eyelashes, which were removed and the underlying tissue histologically analyzed. One year later, the patient came back with even more widespread presence of oral hairs distributed on the gingivae of both arches.
Conclusions:
The occurrence of hairs in the oral cavity is an extremely rare finding. The etiology is still unknown; however, an investigation of systemic health is always desirable because more complex medical conditions may be present and not recognized.
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