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Author Spotlight: Establishing a Reliable Distal MCA Occlusion Model in Mice for Stroke Research
Published on: December 15, 2023
Blind exchange with mini-pinning technique for distal occlusion thrombectomy
Diogo C Haussen1, Alhamza R Al-Bayati1, Brendan Eby1
1Department of Neurology, Emory University, Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, Georgia, USA.
The blind exchange/mini-pinning (BEMP) technique offers a safe and effective method for treating distal occlusions. This approach demonstrated improved first-pass outcomes in stroke patients compared to standard thrombectomy methods.
Area of Science:
- Neurology
- Interventional Neuroradiology
- Vascular Surgery
Background:
- Distal occlusion thrombectomy requires technical advancements for improved efficacy.
- The blind catheter exchange and mini-pinning techniques are introduced for treating distal occlusions.
Purpose of the Study:
- To describe the blind exchange/mini-pinning (BEMP) technique for distal occlusion thrombectomy.
- To evaluate the safety and effectiveness of BEMP compared to standard techniques.
Main Methods:
- Retrospective review of a prospective database (January 2015 - August 2018) for distal occlusions treated with BEMP.
- Detailed description of the BEMP technique involving a Trevo retriever and 3MAX aspiration catheter.
- Comparison of BEMP (n=25) with standard thrombectomy techniques (n=144).
Main Results:
- BEMP was used for distal occlusions, predominantly in distal middle cerebral artery (MCA) segments (M3 occlusions 52% vs 22%).
- Higher rates of first-pass modified Thrombolysis in Cerebral Infarction 2b-3 achieved with BEMP (80% vs 56%, p=0.03).
- Trend towards higher first-pass full reperfusion with BEMP (60% vs 40%, p=0.07); final outcomes were comparable.
Conclusions:
- The BEMP technique is a safe and effective option for treating distal occlusions.
- Further research is recommended to validate these findings.
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