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Updated: Jan 20, 2026
Magnetic Resonance Imaging of Cerebral Aneurysms Using MPRAGE
Published on: May 29, 2025
Aneurysm Architecture: First in vivo Imaging of Human Cerebral Aneurysms with Extravascular Optical Coherence
Karl Hartmann1,2, Klaus-Peter Stein3, Belal Neyazi3
1Department of Neurosurgery, KRH Klinikum Nordstadt, Hannover, Germany, karl.hartmann@krh.eu.
Objective:
The present study was conducted to explore the value of 3-dimensional microscope integrated extravascular optical coherence tomography (OCT) as the first suitable intraoperative imaging modality of cerebral aneurysm (CA) and parent vessel wall morphology.
Methods:
Incidental CAs (n = 16) of the anterior circulation with indication for microsurgical clipping were scanned.
Results:
Analysis revealed that intraoperative OCT achieved to delineate the microstructural composition of the parent vessel in all cases and the CA wall in 68.8%. Clinical relevant characteristics such as thickness, calcification, residual tunica media, and atherosclerotic plaque of CA wall could be demonstrated with high image quality approaching the spatial resolution of histopathology.
Conclusion:
Our findings demonstrate that intraoperative OCT may hold promise as an additional imaging tool during neurovascular procedures.
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