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Published on: January 22, 2020
Association of BMI with Linear Growth and Pubertal Development
Izzuddin M Aris1,2,3, Sheryl L Rifas-Shiman1, Xun Zhang4
1Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.
Higher childhood body mass index (BMI) accelerates early growth but slows adolescent growth and advances puberty. This study examined BMI
Area of Science:
- Pediatric endocrinology
- Growth and development
- Obesity epidemiology
Background:
- The global obesity epidemic impacts child development.
- Understanding BMI's effect on growth is crucial.
Purpose of the Study:
- Investigate the relationship between Body Mass Index (BMI) and subsequent statural growth in children.
- Analyze BMI's influence on growth velocity, final height, and pubertal timing.
Main Methods:
- Utilized multivariable linear and ordinal logistic regression.
- Analyzed data from 18,271 children in Belarus and the United States.
- Examined BMI z-scores from infancy to adolescence.
Main Results:
- Higher BMI z-scores in early life correlated with faster early growth velocity.
- Higher BMI z-scores in middle childhood linked to slower adolescent growth velocity.
- Middle childhood BMI z-scores showed stronger associations with greater standing height, trunk length, and earlier pubertal timing.
Conclusions:
- Higher BMI accelerates early linear growth and trunk length.
- Higher BMI leads to earlier pubertal development and slower adolescent linear growth.
- Findings support BMI's dual role in early and later growth phases.
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